#NSAID CROSS REACTIVITY CHART UPDATE#
#NSAID CROSS REACTIVITY CHART SKIN#

Most of these immune events are mediated by IgE or activated T cells. Reinforce patient education on allergic medication, type of reaction, potential cross-reactive medication and self-management of reaction (if applicable)Дrug allergy is responsible for 6% to 10% of adverse reactions to medications.

#NSAID CROSS REACTIVITY CHART UPDATE#

Identify causative medication based on responsiveness to drug discontinuation and treatmentДocument allergic reaction and update drug allergy information in medical record Provide education to health care providers on an effective management plan of allergic reactionДrug desensitization or graded challenge protocols, if appropriateДЄssess responsiveness to the management plan and revise the plan, if applicable Referals to other providers when appropriate (e.g., allergist) Patient education (e.g., recognition of likely allergenic medication, risk of cross-reactivity with related agents, use of epinephrine self-injectors if applicable) Management of the condition for which the allergic medication was indicated (e.g., treatment of the underlying infection for which the allergenic antibiotic was indicated) Management of the allergic reaction (see Table e-88-3 if patient presents with anaphylaxis)

Need for drug desensitization or induction of drug tolerance (see Tabe e-88-5)

#NSAID CROSS REACTIVITY CHART SKIN#

Medications that may interfere with the identification or treatment of the allergic reaction (e.g., chronic use of antihistamines when skin testing may be warranted chronic beta-blocker use in a patient with anaphylaxis) Severity of the reaction (e.g., localized rash versus a systemic reaction involving one or more organs) Presence of risk factors (see section on Factors related to the Risk or Severity of Allergic Drug Reactions)Д¬o-administration of medications that may increase the risk of an allergic reaction when used in combination (e.g., lamotrigine and valproate) Likelihood of cross-reactivity relative to documented allergy history (e.g., previous documented allergy to penicillin in a patient currently receiving a beta-lactam antibiotic) Timing of the reaction relative to the initiation of each of the patient's current medications Observation of the rash, if applicable (e.g., type of lesion(s), distribution of lesions, presence or absence of oral or genital ulcerations, presence or absence of bullae) Labs (e.g., serum electrolytes, Scr, BUN, LFTs) Subjective findings of the allergic reaction (e.g., shortness of breath, itching, feeling of flushing, lip tingling, nausea, lightheadedness) Medication history (e.g., prescription, OTC, and complementary medications such as herbals)ДЄllergy history (e.g., medications, foods, environmental exposures with descriptions of each reaction) Patient characteristics (e.g., age, race, sex, pregnant) Patient Care Process for the Management of Drug Allergy

Nsaid cross reactivity chart